location: Current position: Home >> Scientific Research >> Paper Publications

Picomolar detection of carcinoembryonic antigen in whole blood using microfluidics and surface-enhanced Raman spectroscopy

Hits:

Indexed by:期刊论文

Date of Publication:2016-03-01

Journal:ELECTROPHORESIS

Included Journals:SCIE、PubMed、Scopus

Volume:37

Issue:5-6

Page Number:786-789

ISSN No.:0173-0835

Key Words:Carcinoembryonic antigen; Microfluidics; SERS; Magnetic nanoparticles

Abstract:Carcinoembryonic antigen (CEA) is a wide-spectrum biomarker. Clinically, we generally use serum sample to detect CEA, which needs to be centrifuged to pretreat the raw blood sample. In this study, we realized direct CEA detection in raw blood samples exploiting microfluidics. The LOD was as low as 10(-12) M.

Pre One:Carcinoma-Associated Fibroblasts Lead the Invasion of Salivary Gland Adenoid Cystic Carcinoma Cells by Creating an Invasive Track

Next One:Manual-slide-engaged paper chip for parallel SERS-immunoassay measurement of clenbuterol from swine hair