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Date of Publication:2022-10-09

Journal:光学精密工程

Affiliation of Author(s):机械工程学院

Issue:5

Page Number:1057-1064

ISSN No.:1004-924X

Abstract:For the requirements of Point-Of-Care Testing (POCT) chips for bonding precision, bonding strength, productivity and biological compatibility, this paper designs a structured energy director and a weld limited joint structure based on ultrasonic bonding. The influence of ultrasonic bonding time and bonding pressure on microchannel's height maintenance was researched, and the optimum processing parameters of precision ultrasonic bonding were determined. After ultrasonic bonding, a high precision microscope, a tensile testing machine and the whole sheep blood were applied to test the microchannel height, bonding strength, microchannel leakproofness and the whole blood driving performance of ultrasonically bonded POCT chips respectively. Experimental results demonstrate that the structured energy director is rational, reliable and easy to integrate each functions. The weld limited joint structure can control the height of microchannel accurately during ultrasonic bonding, the bonding precision of the microchannel is 2 ��m, and the time range of whole blood driving test is less than 20 s. Moreover, the optimum processing parameters are conductive the realization of the high bonding strength more than 2.5 MPa. It concludes that the joint structure and processing parameters have the advantages of high bonding precision, high bonding strength, biological compatibility and uniform welding for POCT chips, and are suitable for the application to medical POCT chips. ? 2016, Science Press. All right reserved.

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