点击次数：

论文类型： 期刊论文

发表时间： 2016-01-27

发表刊物： INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

收录刊物： SCIE、EI、Scopus

卷号： 55

期号： 3

页面范围： 527-533

ISSN号： 0888-5885

摘要： A series of microenvironment-sensitive fluorescent dyes, SA1-4, have been presented, which can light up human serum albumin (HSA) in aqueous media and solid state with colorful emissions as well as dramatic fluorescence enhancements respectively, based on twisted intramolecular charge transfer and molecular rotor strategy. These microenvironment-sensitive SA1-4 exhibited excellent fluorescent capabilities in the fast, convenient, selective, and sensitive recognition of HSA, especially in the quantitative albumin assay in human urine for assessment of kidney function and diagnosis of renal disease. Moreover, SA1-4/HSA complexes could be applied in fluorescence imaging in living cells.