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发布时间：2019-03-09

论文类型：期刊论文

发表时间：2009-10-12

发表刊物：SENSORS AND ACTUATORS B-CHEMICAL

收录刊物：Scopus、EI、SCIE

卷号：142

期号：1

页面范围：191-196

ISSN号：0925-4005

关键字：Fluorescence; Chemosensor; Imaging; Mercury ion; Living cells; Anions

摘要：A fluorescent chemosensor, B2, for Hg(2+) containing a BODIPY fluorophore and carboxyl-thiol metal-bonding moieties was described. B2 exhibits selective fluorescence enhancement (123-fold) toward Hg(2+) over other metal ions. Especially, the fluorescence enhancement was unaffected by anions existing in environment and organism. B2 shows high sensitivity to Hg(2+) in a concentration of ppb range with detection limit of 77 nM. B2-ester, the membrane-permeable ethyl ester, is able to be hydrolyzed to B2 in vivo, and successfully applied to image intracellular Hg(2+) in living cells. (C) 2009 Elsevier B. V. All rights reserved.