|
个人信息Personal Information
副教授
硕士生导师
性别：女
毕业院校：大连理工大学
学位：博士
所在单位：化工海洋与生命学院
电子邮箱：hongyuxue@dlut.edu.cn
扫描关注
Metal-free C-H mercaptalization of benzothiazoles and benzoxazoles using 1,3-propanedithiol as thiol source
点击次数：
论文类型：期刊论文
发表时间：2019-01-29
发表刊物：BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
收录刊物：PubMed、SCIE
卷号：15
页面范围：279-284
ISSN号：1860-5397
关键字：benzothiazole; benzoxazole; C-H functionalization; mercaptalization; 1,3-propanedithiol
摘要：A facile and effective C-H functionalization strategy for the synthesis of 2-mercaptobenzothiazoles and 2-mercaptobenzoxazoles is described. 1,3-Propanedithiol was employed to convert benzothiazoles and benzoxazoles to the corresponding heteroarylthiols in the presence of potassium hydroxide and DMSO. This novel protocol is featured by direct C-H mercaptalization of heteroarenes and a simple reaction system.