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Indexed by:Journal Papers
Date of Publication:2023-05-01
Journal:Digital Medicine
Place of Publication:国际
Volume:9
Issue:4
ISSN No.:2542-629X
Key Words:lean-body-mass-normalized standard uptake value，personalized nuclear medicine，Positron emission tomography/computed tomography diagnosis，standard uptake value
Abstract:Background: The knowledge of [<sup>18</sup>F] fluoro-deoxy-glucose (<sup>18</sup>F-FDG) uptake range in normal torso organ is useful for metabolic disease diagnosis and treatment planning. This study aims to reveal the relationship between torso organ uptakes and personal physiological features, so as to quickly calculate the normal uptake value for patients according to his/her own physiological parameter. Materials and Methods: This study collected 767 <sup>18</sup>F-FDG positron emission tomography/computed tomography (PET/CT) images of normal people. The regions of torso organs were segmented and the mean values of classical body weight-normalized standard uptake value (W-SUV) and lean-body-mass-normalized standard uptake value (L-SUV) were calculated for each organ. The Pearson correlation coefficients and multiple regression formulas were calculated to reveal the influence of physiological features on W-SUV and L-SUV.
DOI number:10.1097/DM-2023-00018
