王洪凯

个人信息Personal Information

教授

博士生导师

硕士生导师

主要任职:医学部副部长

性别:男

毕业院校:清华大学

学位:博士

所在单位:生物医学工程学院

学科:生物医学工程

联系方式:wang.hongkai@dlut.edu.cn

电子邮箱:wang.hongkai@dlut.edu.cn

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From markers to model: Personalized lower limb skeletal reconstruction based on statistical shape models

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论文类型:期刊论文

发表时间:2025-01-01

发表刊物:BIOMEDICAL SIGNAL PROCESSING AND CONTROL

所属单位:[1]Dalian University of Technology [2]Sichuan University

刊物所在地:英国伦敦

学科门类:[1] Engineering, Biomedical

卷号:104

ISSN号:1746-8108

关键字:CONTACT FORCES,MUSCLE,BONES,OPTIMIZATION,MOTION,HIP

摘要:Musculoskeletal models are essential in biomedicine, sports science, and engineering for simulating joint and skeletal dynamics in diagnosis, rehabilitation, and performance analysis. While Computed Tomography and Magnetic Resonance Imaging provide accurate models, they are expensive and time-consuming. Marker-based methods offer a quicker alternative, but challenges persist in balancing accuracy, personalization, and cost. We developed a marker-based method for lower limb skeletal modeling, designed to separately handle posture and shape. Posture is adjusted through kinematic chains, reducing position differences and permitting flexible fitting. The statistical shape model governs the shape modeling, accurately reflecting bone morphology. An iterative algorithm refines the model by aligning it with anatomical landmarks, enabling automatic adaptation to individual subjects. We built a statistical shape model using 81 training cases and conducted three-fold cross-validation. The proposed method improved geometric accuracy over linear scaling (Root Mean Square Error: 3.80 mm, Dice Similarity Coefficient: 0.73, Hausdorff Distance: 19.65 mm). Following this, validation on the West China Hospital dataset confirmed the robustness of the method, the method extended its practical utility by accurately mapping bone and surface landmarks, effectively addressing soft tissue artifacts. Finally, biomechanical analysis using Grand Challenge Competition datasets demonstrated that our method provided more accurate estimates of knee contact forces, reducing Root Mean Square Error by 7.5 %, 28.4 %, and 16.0 % for total, medial, and lateral forces, respectively. The proposed method improves the accuracy of skeletal reconstructions, demonstrating its potential for advancing personalized healthcare and musculoskeletal research.

DOI码:10.1016/j.bspc.2025.107518

影响因子:4.916