王世盛

个人信息Personal Information

副教授

硕士生导师

性别:男

毕业院校:中科院大连化学物理研究所

学位:博士

所在单位:化工学院

学科:药物化学. 药物工程

办公地点:大连理工大学西部校区

联系方式:Office telephone:84986200

电子邮箱:wangss@dlut.edu.cn

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Synthesis of hydroxystilbene derivatives and their antioxidant activity by DPPH method

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论文类型:期刊论文

发表时间:2006-11-01

发表刊物:CHEMICAL RESEARCH IN CHINESE UNIVERSITIES

收录刊物:SCIE、ISTIC、CSCD

卷号:22

期号:6

页面范围:742-746

ISSN号:1005-9040

关键字:polyhydroxystilbene; antioxidant activity; 1,1-diphenyl-2-picrylhydrazyl(DPPH)

摘要:Five hydroxystilbene derivatives were synthesized and their structures were determined using high-resolution mass spectrometry, H-1 NMR, and IR. In this study, the antioxidant activities of eight hydroxystilbenes (five synthesized hydroxystilbene derivatives and three. other compounds) were evaluated with the free radical scavenging model 1,1-diphenyl-2-picrylhydrazyl. It was observed that there exists a very significant linear relationship between the reciprocal of the EC50 value of each of the compounds and the maximum wavelength of the ultraviolet absorption peaks. It is believed that this result will be helpful for the further synthesis of such antioxidants.