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个人信息Personal Information
副教授
硕士生导师
性别：男
毕业院校：中科院大连化学物理研究所
学位：博士
所在单位：化工学院
学科：药物化学. 药物工程
办公地点：大连理工大学西部校区
联系方式：Office telephone：84986200
电子邮箱：wangss@dlut.edu.cn
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Total Synthesis of Two Pyrrole Spiroketal Alkaloids: Pollenopyrroside A and Capparisine B
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论文类型：期刊论文
发表时间：2015-04-01
发表刊物：SYNLETT
收录刊物：SCIE、Scopus
卷号：26
期号：7
页面范围：921-926
ISSN号：0936-5214
关键字：alkaloids; spiroketals; natural products; total synthesis; microwave-assisted reaction
摘要：Pollenopyrroside A and capparisine B, two diastereoisomers of pyrrole spiroketal alkaloids isolated from Brassica campestris pollen and Capparis spinosa, were synthesized by an improved microwave-assisted bishydroxymethylation of pyrrole and acid-catalyzed spirocyclization as key steps with total yields of 2.7 and 8.8%, respectively.