|
个人信息Personal Information
副教授
硕士生导师
性别：男
毕业院校：大连理工大学
学位：博士
所在单位：化工学院
学科：精细化工. 应用化学
办公地点：化工实验楼E506
联系方式：13604282986
电子邮箱：shengzhang@dlut.edu.cn
Copper(II)-Catalyzed and Chelation-Induced Remote C-H Halogenation of Quinolines under Neutral Conditions
点击次数：
论文类型：期刊论文
发表时间：2017-04-24
发表刊物：CHEMISTRYSELECT
收录刊物：SCIE
卷号：2
期号：12
页面范围：3414-3418
ISSN号：2365-6549
关键字：copper(II)-catalyzed; halogenation; neutral condition; chelation induced
摘要：Copper(II)-catalyzed highly regioselective halogenation of 8-acylaminoquinolines was reported in this study. The halogenation of 8-acylaminoquinolines proceeded smoothly in the presence of copper halide (CuBr2 or CuCl2) and potassium halide (KBr or KCl) as the catalyst and the halogen source, respectively, using oxygen in air as the terminal oxidant under neutral conditions to produce the corresponding C-5 position halogenated products in satisfactory to good yields.