Title of Paper:Transition metal-free carboxylation of terminal alkynes with carbon dioxide through dual activation: Synthesis of propiolic acids

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Date of Publication:2019-07-01

Journal:JOURNAL OF CO2 UTILIZATION

Included Journals:SCIE、EI

Volume:32

Page Number:140-145

ISSN No.:2212-9820

Key Words:Carboxylation; CO2 utilization; Organic salt; Dual activation; Propiolic acid

Abstract:The combination use of quaternary ammonium salt and inorganic base in low-boiling-point solvent is presented as a new strategy for terminal alkyne carboxylation with CO2. The carboxylation of terminal alkyne with CO2 proceeded smoothly in the presence of tetra-n-butylammonium acetate and K2CO3 through dual activation under relatively mild conditions to produce the corresponding propiolic acids in satisfactory to excellent yields.