A novel BH3 mimetic S1 potently induces Bax/Bak-dependent apoptosis by targeting both Bcl-2 and Mcl-1.
发布时间：2019-03-12
点击次数：
- 论文类型：
- 期刊论文
- 发表时间：
- 2010-01-01
- 发表刊物：
- International Journal of Cancer. International Journal of Cancer
- 文献类型：
- J
- 卷号：
- 128
- 期号：
- 4
- 页面范围：
- 1724-1735
- 第一作者
- 张志超
- 上一条：Inclusion complex of a Bcl-2 inhibitor with cyclodextrin: characterization, cellular accumulation, and in vivo antitumor activity. Molecular Pharmacology.
- 下一条：3-Thiomorpholin-8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile (S1) Based Molecules as Potent, Dual Inhibitors of B-Cell Lymphoma 2 (Bcl-2) and Myeloid Cell Leukemia Sequence 1 (Mcl-1):