Release Time:2019-03-12  Hits:

Indexed by: Journal Article

Date of Publication: 2017-05-25

Journal: TETRAHEDRON

Included Journals: Scopus、SCIE

Volume: 73

Issue: 21

Page Number: 3031-3035

ISSN: 0040-4020

Key Words: Ir(III) complex; Visible-light; Arylboronic acid; One-pot synthesis; Phenol derivatives

Abstract: The cyclometalated Ir(III) complexes-catalyzed aerobic hydroxylation of arylboronic acids under visible light has been successfully developed. This catalytic system has a broad substrate scope, affording a series of phenols smoothly with the highest isolated yield up to 95%. Moreover, this protocol is capable to synthesize several useful phenols containing bulky moieties, which are potential candidates or intermediates used as pharmaceuticals and functional materials. The Ir(III)-catalyzed hydroxylation of arylboronic acids could be applied in a one-pot synthesis of several important phenol derivatives, including 1,1'-methylene-bis(2-naphthol), 2,3-dihydro-1H-naphtho[2,1-e][1,3]oxazine and a bioactive compound LUF5771. (C) 2017 Elsevier Ltd. All rights reserved.