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A simple and efficient approach for the palladium-catalyzed ligand-free Suzuki reaction in water

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Indexed by:期刊论文

Date of Publication:2012-01-01

Journal:GREEN CHEMISTRY

Included Journals:SCIE、Scopus

Volume:14

Issue:11

Page Number:2999-3003

ISSN No.:1463-9262

Abstract:A general and efficient protocol is described for the palladium-catalyzed ligand-free and aerobic Suzuki reaction in water in the absence of any additive. The results demonstrate that the base played a crucial role in the high efficiency. The Pd(OAc)(2)/(i-Pr)(2)NH/H2O system showed the highest catalytic activity towards the Suzuki reaction of a wide range of aryl halides bearing hydrophilic or hydrophobic groups.

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