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A simple and efficient approach for the palladium-catalyzed ligand-free Suzuki reaction in water

Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2012-01-01

Journal: GREEN CHEMISTRY

Included Journals: Scopus、SCIE

Volume: 14

Issue: 11

Page Number: 2999-3003

ISSN: 1463-9262

Abstract: A general and efficient protocol is described for the palladium-catalyzed ligand-free and aerobic Suzuki reaction in water in the absence of any additive. The results demonstrate that the base played a crucial role in the high efficiency. The Pd(OAc)(2)/(i-Pr)(2)NH/H2O system showed the highest catalytic activity towards the Suzuki reaction of a wide range of aryl halides bearing hydrophilic or hydrophobic groups.

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