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Very Fast, Ligand-Free and Aerobic Protocol for the Synthesis of 4-Aryl-Substituted Triphenylamine Derivatives

Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2011-06-01

Journal: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Included Journals: SCIE

Issue: 16

Page Number: 3009-3015

ISSN: 1434-193X

Key Words: Synthetic methods; Palladium; Boron; Cross coupling; Amines

Abstract: A fast, convenient and ligand-free protocol for the synthesis of a series of 4-aryl-substituted triphenylamine derivatives by a palladium-catalysed aerobic Suzuki reaction of aryl halides with [4-(diphenylamino)phenyl] boronic acid in aqueous iPrOH is described. Importantly, both aryl bromides and heteroaryl halides afforded good to excellent yields under mild conditions.

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