点击次数：

论文类型：期刊论文

发表时间：2013-06-01

发表刊物：ASIAN JOURNAL OF ORGANIC CHEMISTRY

收录刊物：SCIE、Scopus

卷号：2

期号：6

页面范围：514-518

ISSN号：2193-5807

关键字：heterogeneous catalysis; ligand-free; oxygen; palladium; Suzuki reaction

摘要：We report a practical and highly efficient protocol for the synthesis of heterobiaryls by a Pd/C-catalyzed Suzuki reaction under aqueous, aerobic, and ligand-free conditions. This ligand-free catalytic system tolerates a broad range of functional groups in both coupling partners. A variety of heteroaryl halides were coupled with arylboronic acids to give the corresponding heterobiaryls in good to excellent yields. Moreover, the results demonstrated that the Pd/C-catalyzed heterogeneous Suzuki reaction is promoted by oxygen.