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Acid controlled diastereoselectivity in asymmetric aldol reaction of cycloketones with aldehydes using enamine-based organocatalysts

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Indexed by:期刊论文

Date of Publication:2011-01-01

Journal:CHEMICAL COMMUNICATIONS

Included Journals:Scopus、SCIE

Volume:47

Issue:23

Page Number:6716-6718

ISSN No.:1359-7345

Abstract:The example of syn-aldol reaction of cyclohexanone to aldehyde was demonstrated based on chiral diamine organocatalysts and it was realized either by increasing the molecular size of acid additives or by introducing a hydrogen-bond donor into acid additives.

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