崔京南

个人信息Personal Information

教授

博士生导师

硕士生导师

性别:男

毕业院校:日本冈山大学

学位:博士

所在单位:化工学院

学科:精细化工. 应用化学

办公地点:大连理工大学西部校区E209

联系方式:13591789942

电子邮箱:jncui@dlut.edu.cn

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A red emission fluorescent probe for hydrogen sulfide and its application in living cells imaging

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论文类型:期刊论文

发表时间:2013-06-05

发表刊物:TETRAHEDRON LETTERS

收录刊物:SCIE、Scopus

卷号:54

期号:23

页面范围:2980-2982

ISSN号:0040-4039

关键字:Red emission; Fluorescent probe; Hydrogen sulfide; Live cells' imaging

摘要:Hydrogen sulfide has emerged as an important biological messenger and much attention has been paid to the design of fluorescent probes for H2S to meet the requirement of accurate measurement of H2S. In this work, a new red emission fluorescent probe for H2S was developed based on the reduction reaction of azide with H2S to amine with the fluorophore of dicyanomethylenedihydrofuran because of its long excitation and emission wavelength. The probe has a high selectivity for H2S over competitive anions and sulfide-containing analytes. Finally, the probe was applied to sense H2S in living cells. Crown Copyright (C) 2013 Published by Elsevier Ltd. All rights reserved.