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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：日本冈山大学
学位：博士
所在单位：化工学院
学科：精细化工. 应用化学
办公地点：大连理工大学西部校区E209
联系方式：13591789942
电子邮箱：jncui@dlut.edu.cn
Asymmetric bioreduction of substituted acenaphthenequinones using plant enzymatic systems: A novel strategy for the preparation of (+)- and (-)-mono hydroxyacenaphthenones
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论文类型：期刊论文
发表时间：2008-10-01
发表刊物：CHINESE CHEMICAL LETTERS
收录刊物：SCIE、ISTIC、Scopus
卷号：19
期号：10
页面范围：1179-1182
ISSN号：1001-8417
关键字：Bioreduction; Plant enzymes; Acenaphthenequinone; Chiral hydroxyacenaphthenone
摘要：Regio- and enantioselective reduction of substituted acenaphthenequinones were conducted under mild reaction conditions using plant enzymatic systems. A screening of 15 plants allowed the selection of two suitable plants fulfilling enantiocomplementarity. The (+)- and (-)-mono hydroxyacenaphthenones were achieved with high conversion and good enantiomeric purity using peach (Prunus persica (L.) Batsch., conversion 98%, 71% ee) and carrot (Daucus carota L., conversion 95%, 81% ee), respectively. (C) 2008 Jing Nan Cui. Published by Elsevier B. V. on behalf of Chinese Chemical Society. All rights reserved.