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论文类型：期刊论文

发表时间：2019-07-01

发表刊物：POLYHEDRON

收录刊物：SCIE

卷号：166

页面范围：130-136

ISSN号：0277-5387

关键字：Coordination polymer; Copper(II); Chain; Antibacterial activity; Antibacterial mechanism

摘要：One-dimensional copper(II) coordination polymer of [Cu(TDC)(H2O)(2)]center dot H2O (1) has been synthesized and characterized by elemental analysis, X-ray diffraction and thermal gravimetric analysis. 1 consists of [Cu (mu(2)-H2O)(2)](2+) chains with decorative TDC bridges, in which the coordination polyhedron of copper(II) center is distorted octahedral. The antimicrobial activity of 1 against Gram-positive bacteria, Staphylococcus aureus (S. aureus) and Gram-negative bacteria, Escherichia coli (E. coli) was investigated by determining the minimal inhibitory concentration (MIC), the growth curve of bacteria and bacterial reduction assay, and the results indicated that compound 1 possesses higher performance compared with commercial copper nanoparticles and H-2 TDC. The bacteriostatic rate is up to 99.9% against both E. coli and S. aureus when the concentration of compound 1 is upon 300 mu g/mL. The study on antibacterial mechanism showed that the compound 1 favors a slow release of Cu2+ ions and generation of destructive reactive oxygen species leading to excellent and long-term antimicrobial activities. (C) 2019 Elsevier Ltd. All rights reserved.