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论文类型：期刊论文

发表时间：2014-05-01

发表刊物：CARBON

收录刊物：SCIE、EI、Scopus

卷号：71

页面范围：190-195

ISSN号：0008-6223

摘要：The fluorescence of propidium iodide (PI) can be effectively quenched with the addition of graphene oxide (GO) in aqueous solution, due to the formation of a physical adsorption material named GO-PI. A fluorescence enhancement of approximately 80 times can be observed after addition of a certain amount of DNA/RNA into the above-mentioned solution. Meanwhile, it is found that the GO-PI can enter into the nuclei and stain the DNA/RNA of living human breast cancer cells MCF-7, while PI alone cannot cross the cellular membrane in the control experiment, demonstrating GO can be employed to be an efficient PI delivery nanomaterial for live cell staining. (C) 2014 Elsevier Ltd. All rights reserved.