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论文类型：期刊论文

发表时间：2011-05-28

发表刊物：PHYSICAL CHEMISTRY CHEMICAL PHYSICS

收录刊物：PubMed、SCIE、Scopus

卷号：13

期号：20

页面范围：9789-9795

ISSN号：1463-9076

摘要：A series of 1-ethyl-1'-arylmethyl-4,4'-bipyridinium compounds is synthesized, where the aryl is phenyl (BEV), 2-naphthyl (NEV), 2-anthracenyl (AEV) or 1-pyrenyl (PEV). Among them, PEV and AEV can bind with calf thymus DNA mainly through intercalation and groove-binding modes, and both of them can be observed to photocleave plasmid pBR 322 DNA significantly under irradiation with a xenon arc lamp. After inclusion of cucurbit[8]uril (CB[8]), all of the aromatic donor-viologen acceptor compounds exhibit efficient DNA photocleavage ability. The reason is that CB[8] can inhibit the intramolecular backwards electron transfer in the aromatic donor-viologen acceptor molecule, prolonging the lifetime of the charge separated excited state to some extent. These studies bring a new subject in DNA photocleavage research and a potential application of the host-guest supramolecular system.