Hits:

Indexed by:期刊论文

Date of Publication:2018-01-01

Journal:SYNTHESIS-STUTTGART

Included Journals:SCIE、EI、Scopus

Volume:50

Issue:2

Page Number:341-348

ISSN No.:0039-7881

Key Words:omega-substituted biuret; N-monosubstituted urea; potassium cyanate; dicyanic acid; selective reactions

Abstract:A novel, simple, and highly efficient method has been designed for the synthesis of -substituted arylbiurets in a one-pot reaction. The primary features of this protocol include readily available starting materials, an easy work-up procedure, and yields of 51 to 87%. omega-Substituted arylbiurets can be selectively prepared with an excess of potassium cyanate (KOCN). However, use of an excess of glacial acetic acid (AcOH) switches the reaction towards the formation of N-monosubstituted urea.