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PdCl2-catalyzed cross-coupling reaction of arylacetylene iodides with arylboronic acids to diarylacetylenes

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Indexed by:期刊论文

Date of Publication:2010-07-14

Journal:TETRAHEDRON LETTERS

Included Journals:SCIE、Scopus

Volume:51

Issue:28

Page Number:3626-3628

ISSN No.:0040-4039

Key Words:Suzuki cross-coupling; Diarylacetylene; Palladium chloride; Alkynylation

Abstract:Anew Suzuki-type cross-coupling reaction between 1-iodo-2-arylalkynes and arylboronic acids to afford a wide variety of functionalized diarylacetylenes in a mild reaction condition was developed. The reaction was catalyzed by a small amount of a structurally simple, commercially available, and stable PdCl2. This unique sp-sp(2) carbon-carbon bond formation provides a new protocol for the synthesis of diarylacetylenes, which is a new addition to the Suzuki cross-coupling reaction. (C) 2010 Elsevier Ltd. All rights reserved.

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