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Real-time biodetection using a smartphone-based dual-color surface plasmon resonance sensor.
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论文类型: 期刊论文
发表时间: 2018-01-01
发表刊物: Journal of biomedical optics
收录刊物: PubMed、SCIE
卷号: 23
期号: 4
页面范围: 1-6
ISSN号: 1560-2281
关键字: optical fiber sensor; surface plasmon resonance; biological sensing and sensors; visibility and imaging
摘要: We proposed a compact and cost-effective red-green dual-color fiber optic surface plasmon resonance (SPR) sensor based on the smartphone. Inherent color selectivity of phone cameras was utilized for real-time monitoring of red and green color channels simultaneously, which can reduce the chance of false detection and improve the sensitivity. Because there are no external prisms, complex optical lenses, or diffraction grating, simple optical configuration is realized. It has a linear response in a refractive index range of 1.326 to 1.351 (R2=0.991) with a resolution of 2.3*10-4RIU. We apply it for immunoglobulin G (IgG) concentration measurement. Experimental results demonstrate that a linear SPR response was achieved for IgG concentrations varying from 0.02 to 0.30mg/ml with good repeatability. It may find promising applications in the fields of public health and environment monitoring owing to its simple optics design and applicability in real-time, label-free biodetection. (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

刘云

副教授   博士生导师   硕士生导师

性别: 男

毕业院校:大连理工大学

学位: 博士

所在单位:物理学院

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