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发表时间：2016-01-01

发表刊物：口腔医学研究

卷号：32

期号：7

页面范围：676-680

ISSN号：1671-7651

摘要：Objective:To assess the osseointegration of porous titania(TiO_2)coating
   with a novel cortex-like morphology by micro-CT.Methods:Cortex-like
   morphology Ti surface was produced by MAO,and SLA surface was used as
   control.The surface features were evaluated by scanning electron
   microscope(SEM)and contact Angle. Thirty-six threaded implants were
   placed in the femoral condyles of 18male New Zealand White
   rabbits.Trabecular bone morphology parameters were analyzed after
   implantation 4weeks and 8weeks by Micro-CT.Results: Morphology
   microstructure of MAO cortex-like was composed of microscale and
   nanoscale structure,with better wettability and contact
   Angle(6.91.14)°.Along with the time of bone healing,the BV/TV,Tb.N,Tb.Th
   and Conn.Dn were increased,while SMI and Tb.Sp were decreased.At 4th
   week,statistical significances were detected in BV/TV and SMI(P<0.05).At
   8th week,statistical significances were detected in BV/TV,Tb.N, Tb.Sp
   and Conn.Dn(P<0.05).Cortex-like morphology exhibited more continuous
   bone apposition.Conclusion: The cortex-like morphology of titanium with
   microscale and nanoscale topologic structure can improve the
   osseointegration of Ti implant and has good biocompatibility.

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