location: Current position: Home >> Scientific Research >> Paper Publications

Temperature insensitive optical biosensor based on polymer waveguide microring

Hits:

Indexed by:期刊论文

Date of Publication:2015-11-10

Journal:Guangxue Xuebao/Acta Optica Sinica

Included Journals:EI、PKU、ISTIC

Volume:35

Issue:11

ISSN No.:02532239

Abstract:The temperature sensitivity is the key factor to influence the performance of optical biosensor based on waveguide microring. According the resonant equation of the waveguide microring, the mechanism inducing the temperature sensitivity is analyzed. The sandwich polymer substrate of SU8-NOA61-SU8 is employed to replace the conventional silicon substrate. The thermo-optic effect of the waveguide is counteracted by the thermoexpansion effect of the sandwich polymer substrate, resulting in the temperature insensitivity of the all polymer waveguide microring biosensor. The optimized thicknesses of the sandwich substrate for the temperature insensitive microring sensor are obtained by the design with ANSYS software. The films of SU8 and NOA61 are prepared with the spin coating technique. The controllable thickness precisions of SU8 and NOA61 films are 0.07  m@20r/min and 0.34  m@20r/min, respectively. The temperature sensitivity and the detection limit of the polymer waveguide microring biosensor with the sandwich polymer substrate are as same as the performance of the one on the silicon substrate with a temperature controller. ? 2015, Chinese Laser Press. All right reserved.

Pre One:Quantitative determination of the beta-2-microglobulin monomer by gel filtration chromatography [基于凝胶过滤色谱的β2微球蛋白标准品单体定量检测方法]

Next One:Study of hydrophobic interaction between immobilized ligands and proteins using an improved docking method