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论文类型：期刊论文

发表时间：2009-07-24

发表刊物：JOURNAL OF CHROMATOGRAPHY A

收录刊物：PubMed、SCIE

卷号：1216

期号：30

页面范围：5647-5654

ISSN号：0021-9673

关键字：Bisphenol A; Liquid chromatography; Molecular imprinted polymer; Solid-phase microextraction

摘要：Molecular imprinted polymer (MIP) as solid-phase microextraction (SPME) fibers coating has gained great attention in recent years. In this study, a simple preparation approach for bisphenol A (BPA) MIP coating with controlled thickness on fused-silica capillaries was developed. A capillary was inserted into a larger bore capillary to form a sleeve as mold. The prepolymer solution containing the template BPA was introduced into the interspace between the two capillaries for polymerization under photoirradiation. The larger bore capillary was removed away after the polymerization, and MIP coating with certain thickness on the surface of the inserted capillary was obtained. SPME conditions based on the MIP-coated fibers were optimized, and the extraction performance of the fibers with different thickness coating was compared. Finally, the MIP fibers were used for selective extraction of BPA spiked in tap water, human urine, and milk samples. The average recoveries of spiked BPA in the three samples were 92.5%, 81.6%, and 87.5%, respectively. The present analytical performance is not up to par for applicability to real environmental matrices. Further improvement will be necessary for analysis of real complex samples. (C) 2009 Elsevier B.V. All rights reserved.