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论文类型：期刊论文

发表时间：2023-05-30

发表刊物：ACS Biomaterials Science & Engineering

收录刊物：SCI

卷号：9

期号：6

页面范围：3227-3238

ISSN号：2373-9878

关键字：magnesium alloy, calcium phosphate, stearic acid, corrosion resistance, biocompatibility

摘要：Magnesium (Mg) alloys, a degradable material, have been studied for medical applications due to their excellent mechanical and chemical properties. However, their applications are limited by rapid corrosion. In this work, stearic acid and sodium stearate were used to treat the silane-induced calcium phosphate dihydrate coating to improve its protection for the Mg alloy further without changing the bone-like structure of calcium phosphate. The different effects of stearic acid treatment and sodium stearate treatment were compared. Electrochemical test and immersion test results confirmed that the corrosion resistance of the stearic acid-treated composite coating was greatly enhanced with a reduced corrosion current density by 3 orders of magnitude and hydrogen evolution reduced to 1/25 after 14 days. The stearic acid-treated coating also exhibited improved in vitro biocompatibility corroborated by promoted cell viability and better cell morphology.

DOI码：10.1021/acsbiomaterials.3c00003

影响因子：5.5