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发布期刊链接：https://www.sciencedirect.com/science/article/pii/S2589152922000023

论文类型：期刊论文

发表时间：2022-01-10

发表刊物：Materialia

收录刊物：SCI

卷号：21

ISSN号：2589-1529

关键字：Magnesium alloy, Composite coating, Corrosion resistance, Biocompatibility

摘要：In order to improve the corrosion resistance and biocompatibility of magnesium (Mg) alloy and reduce the rapid degradation rate, which limits its biomedical application, a calcium phosphate (CaP)/graphene oxide (GO) composite coating based on polydopamine (PDA) was prepared. PDA was used as a pretreatment layer to induce biomimetic deposition of CaP, and then GO as a sealing layer was spin-coated with ethanol and water as dispersants, respectively. The composition, morphology, corrosion resistance and biocompatibility of the composite coating were characterized and tested. The result of electrochemical and immersion test shows that the corrosion resistance of the PDA/CaP/GO composite coating was significantly enhanced. Meanwhile, the in vitro cell experiments indicates that the composite coating promotes cell adhesion and improves biocompatibility. Moreover, the corrosion resistance and biocompatibility of the PDA/CaP/GO composite coating with water as the dispersant is better than that with ethanol, and is significantly improved compared with the Mg alloy, indicating the good potential for development in the biomedical field.

DOI码：10.1016/j.mtla.2022.101315

影响因子：2.9