王心莲

个人信息Personal Information

助理教授

硕士生导师

性别:女

毕业院校:中国科学院大学

学位:博士

所在单位:生物工程学院

办公地点:生物工程楼505

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王心莲,大连理工大学生物工程学院助理教授,硕士生导师。林岛学者,大连市青年才俊。

2025年博士毕业于中国科学院国家纳米科学中心,师从赵宇亮院士团队。研究方向聚焦于肿瘤免疫治疗与疫苗开发,包括循环肿瘤细胞类器官构建、基于生物信息学的肿瘤免疫微环境解析、肿瘤个性化疫苗开发等。在Advanced Functional Materials、ACS Nano、Nano Today等权威SCI期刊发表论文20余篇。

代表性文章:

[1] Wang X#, Gao X#, Wang L, Lin J, Liu Y. Advances of nanotechnology toward vaccine development against animal infectious diseases [J]. Adv Funct Mater, 2023, 33(46): 2305061.

[2] Wang X#, Lin J#, Yin D#, Li X, Lang Z, Zhang G, Xue Y, Li S, Zhang X, Han B, Li F, Liu Y. Inhalable multilevel responsive microspheres for radiation-induced lung injury [J]. Nano Res, 2025, 18(5): 94907339.

[3] Gao X#, Wang X# (co-first author), Li S, Rahman M, Xu S, Liu Y. Nanovaccines for advancing long-lasting immunity against infectious diseases [J]. ACS Nano, 2023, 17(24): 24514-24538.

[4] Wang L#, Xue Y#, Wang X# (co-first author), Pan Y, Li S, Mei J, Jiang S, Zheng Q, Liu Y, Liu Y, Yuan J, Ma Y. DEPDC1 is a potential therapeutic target in lung adenocarcinoma [J]. Nano Today, 2024, 56: 102249.

[5] Lin J, Wang X, Ni D, Chen Y, Chen C, Liu Y. Combinational gene therapy toward cancer with nanoplatform: strategies and principles [J]. ACS Mater Au, 2023, 3(6): 584-599.

[6] Jiang J#, Zheng H#, Wang Z, Wang X, Xie Q, Liu X, Yang Q, Cai X, Gao X, Li R, Chen C. Intracellular dehydrogenation catalysis leads to reductive stress and immunosuppression [J]. Nat Nanotechnol, 2025, 20(4): 554.

[7] Sun D, Wang H, Liu J, Wang X, Guo H, Xue L, Li L, Li J, Zhang B, Xue Y, Li S, Liu Y. An enzyme cross-linked hydrogel as a minimally invasive arterial tissue sealing and anti-adhesion barrier [J]. Nano Today, 2022, 44: 101467.

[8] Chen Y#, Xue Y#, Liu W#, Li S, Wang X, Zhou W, Zhang G, Liu K, Zhang H, Zhao Y, Chen C, Liu Y. Untethered artificial muscles powered by wearable sweat-based energy generator [J], Nano Today, 2023, 49: 101765.


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