Asymmetric bioreduction of substituted acenaphthenequinones using plant enzymatic systems: A novel strategy for the preparation of (+)- and (-)-mono hydroxyacenaphthenones
发布时间：2019-03-10
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- 论文类型：
- 期刊论文
- 发表时间：
- 2008-10-01
- 发表刊物：
- CHINESE CHEMICAL LETTERS
- 收录刊物：
- Scopus、ISTIC、SCIE
- 文献类型：
- J
- 卷号：
- 19
- 期号：
- 10
- 页面范围：
- 1179-1182
- ISSN号：
- 1001-8417
- 关键字：
- Bioreduction; Plant enzymes; Acenaphthenequinone; Chiral hydroxyacenaphthenone
- 摘要：
- Regio- and enantioselective reduction of substituted acenaphthenequinones were conducted under mild reaction conditions using plant enzymatic systems. A screening of 15 plants allowed the selection of two suitable plants fulfilling enantiocomplementarity. The (+)- and (-)-mono hydroxyacenaphthenones were achieved with high conversion and good enantiomeric purity using peach (Prunus persica (L.) Batsch., conversion 98%, 71% ee) and carrot (Daucus carota L., conversion 95%, 81% ee), respectively. (C) 2008 Jing Nan Cui. Published by Elsevier B. V. on behalf of Chinese Chemical Society. All rights reserved.
- 第一作者
- Tong, Lian Peng
- 合写作者
- Wang, Xing Yong,Qian, Xu Hong,Cui, Jing Nan,Ren, Wei Min
- 通讯作者
- Cui, JN (reprint author), Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116012, Peoples R China.