Indexed by:期刊论文

Date of Publication:2017-06-14

Journal:TETRAHEDRON LETTERS

Included Journals:SCIE、Scopus

Volume:58

Issue:24

Page Number:2351-2354

ISSN No.:0040-4039

Key Words:Hydrazine; Hydrazinolysis; Cinnamoyl; pi-pi conjugate

Abstract:Herein we discovered that a Nile Red-based probe with a cinnamoyl unit was highly selective and sensitive to N2H4. Hydrazinolysis by N2H4 would release a hydroxyl substituted Nile Red and result in remarkable fluorescence quench. Importantly, Cys/Hcy would not interrupt the N2H4 recognition. This is because, for this probe, the combination of the pi-pi conjugate system can stabilize the ethylene union, which results in the nucleophilic addition of the thiol group of Cys/Hcy becomes non -effective. (C) 2017 Elsevier Ltd. All rights reserved.