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Terminal alkyne substituted O-6-benzylguanine for versatile and effective syntheses of fluorescent labels to genetically encoded SNAP-tags
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Indexed by:期刊论文

Date of Publication:2015-02-26

Journal:RSC ADVANCES

Included Journals:SCIE、EI、Scopus

Volume:5

Issue:30

Page Number:23646-23649

ISSN No.:2046-2069

Abstract:We have developed a terminal alkyne substituted O6-benzylguanine, named PYBG, as a versatile precursor to be facilely conjugated with various fluorescent dyes through 'Click chemistry' and Sonogashira coupling reactions. These fluorescent PYBG derivatives specifically and efficiently label the target genetically encoded SNAP-tags in live cells.

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Gender:Male

Alma Mater:Dalian University of Technology

Degree:Doctoral Degree

School/Department:State Key Laboratroy of Fine Chemicals

Discipline:Applied Chemistry. Fine Chemicals. Biochemical Engineering

Business Address:West Campus E-204

Contact Information:xiaoyi@dlut.edu.cn 0411-84986251

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