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Activatable Rotor for Quantifying Lysosomal Viscosity in Living Cells
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Indexed by:Journal Article

Date of Publication:2013-02-27

Journal:JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Included Journals:Scopus、PubMed、EI、SCIE

Volume:135

Issue:8

Page Number:2903-2906

ISSN:0002-7863

Abstract:We have developed Lyso-V, the first fluorescent probe of lysosomal viscosity. Because of its lysosome-actived fluorescence characteristics, Lyso-V has proved to be an ideal lysosomal tracer with high spatial and temporal resolution under laser confocal microscopy. More importantly, Lyso-V shows its practical applicability in real-time quantification of lysosomal viscosity changes in live cells through fluorescence lifetime imaging microscopy.

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Gender:Male

Alma Mater:Dalian University of Technology

Degree:Doctoral Degree

School/Department:State Key Laboratroy of Fine Chemicals

Discipline:Applied Chemistry. Fine Chemicals. Biochemical Engineering

Business Address:West Campus E-204

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