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A Lysosome-Targetable and Two-Photon Fluorescent Probe for Monitoring Endogenous and Exogenous Nitric Oxide in Living Cells
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Indexed by:Journal Article

Date of Publication:2012-10-24

Journal:JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Included Journals:Scopus、ESI高被引论文、PubMed、EI、SCIE

Volume:134

Issue:42

Page Number:17486-17489

ISSN:0002-7863

Abstract:A lysosome-specific and two-photon fluorescent probe, Lyso-NINO, demonstrates high selectivity and sensitivity toward NO, lower cytotoxicity, and perfect lysosomal localization. With the aid of Lyso-NINO, the first capture of NO within lysosomes of macrophage cells has been achieved using both two-photon fluorescence microscopy and flow cytometry.

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Gender:Male

Alma Mater:Dalian University of Technology

Degree:Doctoral Degree

School/Department:State Key Laboratroy of Fine Chemicals

Discipline:Applied Chemistry. Fine Chemicals. Biochemical Engineering

Business Address:West Campus E-204

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