
教授 博士生导师 硕士生导师
性别:男
毕业院校:大连理工大学
学位:博士
所在单位:化工学院
学科:应用化学
精细化工
生物化工
办公地点:西校区E-204
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发布时间:2019-03-09
论文类型:期刊论文
发表时间:2013-02-27
发表刊物:JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
收录刊物:Scopus、PubMed、EI、SCIE
卷号:135
期号:8
页面范围:2903-2906
ISSN号:0002-7863
摘要:We have developed Lyso-V, the first fluorescent probe of lysosomal viscosity. Because of its lysosome-actived fluorescence characteristics, Lyso-V has proved to be an ideal lysosomal tracer with high spatial and temporal resolution under laser confocal microscopy. More importantly, Lyso-V shows its practical applicability in real-time quantification of lysosomal viscosity changes in live cells through fluorescence lifetime imaging microscopy.