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论文类型： 期刊论文

发表时间： 2012-10-24

发表刊物： JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

收录刊物： SCIE、EI、PubMed、ESI高被引论文、Scopus

卷号： 134

期号： 42

页面范围： 17486-17489

ISSN号： 0002-7863

摘要： A lysosome-specific and two-photon fluorescent probe, Lyso-NINO, demonstrates high selectivity and sensitivity toward NO, lower cytotoxicity, and perfect lysosomal localization. With the aid of Lyso-NINO, the first capture of NO within lysosomes of macrophage cells has been achieved using both two-photon fluorescence microscopy and flow cytometry.