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Avapritinib Carries the Risk of Drug Interaction via Inhibition of UDP-Glucuronyltransferase (UGT) 1A1

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Date of Publication:2024-01-01

Journal:CURRENT DRUG METABOLISM

Volume:25

Issue:3

Page Number:197-204

ISSN No.:1389-2002

Key Words:CLEARANCE; ENZYME; GLUCURONIDATION; HEPATOTOXICITY; HUMAN LIVER; MICROSOMES; PREDICTION; PROBES; SELECTIVITY; SUBSTRATE

Pre One:Characterization of Dicaffeoylspermidine Derivatives from Wolfberry as Potent and Selective Inhibitors of Human Cytochrome P450 46A1 In vitro.

Next One:Drug-drug interaction potentials of tucatinib inhibition of human UDP-glucuronosyltransferases.
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