个人信息Personal Information
副教授
博士生导师
硕士生导师
性别:男
毕业院校:中国协和医科大学
学位:博士
所在单位:生物工程学院
学科:生物化工. 微生物学. 微生物与生化药学
办公地点:辽宁省大连市高新园区凌工路2号大连理工大学西部校区生物工程学院309室
联系方式:辽宁省大连市高新园区凌工路2号大连理工大学生物工程学院
电子邮箱:yshdong@dlut.edu.cn
虎杖发酵液中白藜芦醇的分离纯化工艺研究
点击次数:
发表时间:2022-10-06
发表刊物:中草药
期号:2
页面范围:223-227
ISSN号:0253-2670
摘要:Objective To isolate and purify resveratrol fromermentation broth of Polygonum cuspi-datum. Methods Macroporous resin and polyamide column chromatography were combined to purify res- veratrol from the extract in fermentation broth of P. cuspidatum, and the adsorption dynamics of resvera-trol was evaluated. Results Apparent static adsorptive capacities of resveratrol on macroporous resin and polyamide were 11.70 and 57.9 mg/g, respectively, and apparent dynamic adsorptive capacities were 12.47 and 58.98 mg/g,respectively. Both of the adsorption isotherms correlate well with Langmuir type. After macroporous resin and polyamide two-step column chromatography, the purity of resveratro] reached 95.8%, with the yield of 69.8%. Conclusion It is proved the method is potential for industrial applica-tion clue to its simple procedure, lower cost as well as high purity and yield of resveratrol.
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