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论文类型：应用研究

发表时间：2025-01-09

发表刊物：Diabetes Obes Metab

收录刊物：SCIE

所属单位：大连理工附属中心医院（大连市中心医院）

刊物所在地：英国

学科门类：医学

项目来源：辽宁省博士启动基金

页面范围：1-9

关键字：abdominal fat, bariatric surgery, obesity, subcutaneous fat, weight loss

教研室：外科

摘要：Background: The body weight following bariatric surgery is a primary concern for both healthcare professionals and surgical candidates. However, it remains unclear whether variations in preoperative fat distribution influence weight loss outcomes.
Objective: The aim of this study was to evaluate the effect of abdominal fat distribution on postoperative weight loss and body mass index (BMI) reduction, and to clarify the role of different fat depots in weight loss outcomes.
Methods: Preoperative data from patients with overweight or obesity, along with their weight records at 1, 2 and 5 years following surgery, were retrospectively collected. Multiple levels of abdominal fat areas were measured using computerized
tomography imaging. Statistical analyses included Pearson's correlation coefficients, multiple linear regressions, ridge regressions, decision tree regressions and paired tests to evaluate the associations and influences.
Results: A total of 139 patients were initially included. The statistical analysis results indicated that umbilical subcutaneous adipose tissue (SAT) was an independent factor influencing weight and BMI loss at the 1-year follow-up (n = 67, p < 0.01). Furthermore, umbilical SAT demonstrated significant correlations with sustained BMI reduction over the long term.
Conclusion: Umbilical SAT is a significant factor in postoperative weight and BMI loss. Patients with greater SAT may experience more substantial weight and BMI reductions following surgery, offering new insights into personalized weight loss strategies and alternative approaches for assisted weight loss.

DOI码：10.1111/dom.16172

影响因子：5.7