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个人信息Personal Information
副教授
硕士生导师
性别：女
毕业院校：大连理工大学
学位：博士
所在单位：化工学院
学科：药物化学. 药物工程
办公地点：G302
联系方式：13504248501
电子邮箱：yueqingli@dlut.edu.cn
扫描关注
Synthesis of 2-(5-hydroxymethyl-2-formylpyrrol-1-yl)propionic acid lactone
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论文类型：期刊论文
发表时间：2012-05-01
发表刊物：CHEMISTRY OF NATURAL COMPOUNDS
收录刊物：SCIE、Scopus
卷号：48
期号：2
页面范围：194-197
ISSN号：0009-3130
关键字：alkaloid; L-alanine; transesterification; lactone
摘要：2-(5-Hydroxymethyl-2-formylpyrrol-1-yl)propionic acid lactone was synthesized in six steps with a 17.0% overall yield, starting from L-alanine. The synthetic route involved the Clauson-Kaas reaction, Vilsmeier reaction, and transesterification. The transesterification was the key step in the formation of the target compound.