袁文杰

个人信息Personal Information

副教授

博士生导师

硕士生导师

主要任职:生物工程学院副院长

性别:女

毕业院校:大连理工大学

学位:博士

所在单位:生物工程学院

学科:生物化工

办公地点:生物楼317

联系方式:0411-84706802 13591380715

电子邮箱:ywj@dlut.edu.cn

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个人简介Personal Profile

袁文杰,博士,教授,博士生导师,生物工程学院副院长。从事微生物生理代谢方面的相关研究,从微生物菌株选育到发酵过程优化,以及利用合成生物学方法对微生物进行改造,使其满足目标代谢产物高效生产的需要。研究的目标集中在生物能源及生物医药产品。取得的研究结果已在Bioresour TechnolJ Biol Chem等国内外期刊发表论文60余篇,授权专利10余项,获辽宁省科技进步奖一等奖、辽宁省自然科学成果一等奖,教育部科技进步二等奖、日内瓦专利金奖、生物工程学报优秀论文奖等多项。承担国家自然科学基金、国家重点研发项目子课题、863项目子课题、国际合作项目子课题、中国博士后基金、辽宁省博士启动基金、企业委托项目等十余项,完成产业化项目2项。

代表性论文

(1) Cong Du, Yimin Li, Ruijuan Xiang, Ying He, Hao Sun, Huanan Wang,  Wenjie Yuan*. Co-utilization of multiple lignocellulose-derived sugars and inhibitors by the robust mutant Kluyveromyces marxianus through adaptive laboratory evolution. Fuel, 2021, online.

(2) Cong Du, Yimin Li, Han Zong, Tangguo Yuan, Wenjie Yuan, Yu Jiang.

Production of bioethanol and xylitol from non-detoxified corn cob via a twostage fermentation strategy. Bioresource Technology, 2020, 310:123427.

(3) Xuze Pei, Yimin Li, Cong Du, Tangguo Yuan, Chao Fan, Hao Hong, Wenjie Yuan*. Production of L-alanyl-L-glutamine by immobilized Escherichia coli expressing amino acid ester acyltransferase. Applied Microbiology and Biotechnology, 2020, 104(16): 6967-6976.

(4) Cong Du, Yimin Li, Xiaoyang Zhao, Xuze Pei, Wenjie Yuan*, Fengwu Bai, Yu Jiang. The production of ethanol from lignocellulosic biomass by Kluyveromyces marxianus CICC 1727-5 and Spathaspora passalidarum ATCC MYA-4345. Appl Microbiol Biotechnol. 2019, 103:2845-2855

(5) Wenjie Yuan, Shuguang Guo, Jiaoqi Gao, Mingming Zhong, Gonghong Yan, Wangmeng Wu, Yapeng Chao, Yu Jiang *. General control nonderepressible 2 (GCN2) kinase inhibits target of rapamycin cComplex 1 in response to amino acid starvation in Saccharomyces cerevisiae. Journal of Biological Chemistry, 2017, 292(7): 2660~2669.

(6) Yimin Li, Yuan wenjie*, Jiaoqi Gao, Chao Fan, Wenzhong Wu, Fengwu Bai. Production of L-alanyl-L-glutamine by recycling E. coli expressing a-amino acid ester acyltransferase. Bioresource Technology 2017, 245:1603–1609

(7) Jiaoqi Gao, Hualiang Feng, Yimin Li, Shengbo Hou, Wenjie Yuan*,Shijun Zhong, Fengwu Bai. Enhanced fermentative performance under stresses of multiple lignocellulose-derived inhibitors by overexpression of a typical 2-Cys peroxiredoxin from Kluyveromyces marxianus. Biotechnol Biofuels, 2017, 10: 80-79.

(8) Jiaoqi Gao, Yimin Li, Ruijuan Xiang, Shegnbo Hou, Wenjie Yuan*, Shijun Zhong, Fengwu Bai. Transcriptional analysis of Kluyveromyces marxianus for ethanol production from inulin using consolidated bioprocessing technology. Biotechnol Biofuels, 2015, 8: 115-132.



  • 教育经历Education Background
  • 工作经历Work Experience
  • 研究方向Research Focus
  • 社会兼职Social Affiliations
  • (1)生物能源 (2)微生物代谢工程 (3)合成生物学