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论文类型：期刊论文

发表时间：2020-01-01

发表刊物：ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

收录刊物：PubMed、SCIE

卷号：27

期号：3

页面范围：2721-2729

ISSN号：0944-1344

关键字：Organophosphate esters; Human serum; Bohai Bay; Demographic characteristics

摘要：Organophosphate esters (OPEs), as a class of emerging flame retardant and plasticizers, have attracted particular attention due to their ubiquitous existence in the environment and potential effects on human health. Here, we investigated the levels of OPEs in human serum and examined the role of demographic variables on the body burden of such compounds. Of 11 OPEs screened, 8 were detected in human serum samples collected froma population (n = 89) in Bohai Bay, North China. The Sigma OPE concentrations ranged from 4.7 to 948 ng/g lipid weight (lw), with a median concentration of 243 ng/g lw. Tris(2-chloroethyl)phosphate (TCEP) was identified as the most abundant OPEs with a median concentration of 214 ng/g lw. The concentrations of the triphenyl phosphate (TPhP) in older adults were higher than those in young adults (p < 0.05), and lower concentrations of tri-iso-butyl phosphate (TIBP) were observed in female samples compared to males. Furthermore, significant differences were observed in tri-n-propyl phosphate (TPrP) concentrations between urban and rural residence groups (p < 0.05). This study provides important information on the accumulation potential of OPEs in human bodies and suggests the need for further investigation to understand the potential human health risk.