LIU Chengde   

Associate Professor
Supervisor of Doctorate Candidates
Supervisor of Master's Candidates

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柳承德,副教授,硕士生导师,博士生导师,隶属于化工学院高分子材料系蹇锡高院士课题组。主要研究工作为杂萘联苯聚芳醚骨植入材料的合成及表面改性。通过分子结构设计、优化聚芳醚的合成方法及开发新型纯化技术,获得力学性能和生物学性能满足聚芳醚生物材料要求的医用杂萘联苯聚芳醚,完成中试实验研究。对聚芳醚进行生物功能化表面改性,改善了聚芳醚材料的生物相容性,并赋予其成骨活性,抗菌功能及局部治疗功能。在国内外重要学术期刊上共发表论文20余篇。


代表性学术论文:

1Yizheng Li, Chengde Liu*, Xitong Cheng, Jinyan Wang, Yue Pan, Cheng Liu, Shouhai Zhang, Xigao Jian*. PDA-BPs integrated mussel-inspired multifunctional hydrogel coating on PPENK implants for anti-tumor therapy, antibacterial infection and bone regeneration. Bioactive Materials, 2023, 27: 546–559.

2. Xitong Cheng, Xiao Yang, Chengde Liu*, Yizheng Li, Yangyang Zhang, Jinyan Wang,* Xingdong Zhang, and Xigao Jian. Stabilization of Apatite Coatings on PPENK Surfaces by Mechanical Interlocking to Promote Bioactivity and Osseointegration In Vivo. ACS Appl. Mater. Interfaces 2023, 15, 697−710.

3. Xitong Cheng, Yizheng Li, Wentao Liu, Shouhai Zhang, Chengde Liu*, Jinyan Wang*, Xigao Jian. Phosphonate-functionalized poly(phthalazinone ether ketones) induce the formation of apatite coatings for enhanced biocompatibility and osteogenic activity. ACS Applied Polymer Materials 2022, 4, 2562 .

4. Yizheng Li, Chengde Liu*, Xitong Cheng, Ali Zhang, Wentao Liu, Shouhai Zhang, Xigao Jian*. Tunicate inspired gelatin-based tough hydrogel wound dressing containing twisted phthalazinone with adhesive, self-healing and antibacterial properties. International Journal of Biological Macromolecules, 2022, 218, 639.

5. Wentao Liu, Chengde Liu, Cheng Liu, Yizheng Li, Liang Pan, Jinyan Wang and Xigao Jian*. Surface chemical modification of poly(phthalazinone ether nitrile ketone) through rhBMP-2 and antimicrobial peptide conjugation for enhanced osteogenic and antibacterial activities in vitro and in vivo. Chemical Engineering Journal 2021, 424, 130321. (在蹇院士和柳承德共同指导下,刘文韬博士完成本篇论文)

6. Chengde Liu, Liang Pan, Cheng Liu, Wentao Liu, Yizheng Li, Xitong Cheng and Xigao Jian*. Enhancing Tissue Adhesion and Osteoblastic Differentiation of MC3T3-E1 Cells on Poly(aryl ether ketone) by Chemically Anchored Hydroxyapatite Nanocomposite Hydrogel Coating. Macromolecular bioscience 2021, 21(7), 2100078.

7. Wentao Liu, Han Wang, Cheng Liu, Jinyan Wang, Xitong Cheng, Chengde Liu*, Liyuan Qiao, Shouhai Zhang, Xigao Jian*. RhBMP-2 immobilized on poly(phthalazinone ether nitrile ketone) via chemical and physical modification for promoting in vitro osteogenic differentiation. Colloids and Surfaces B: Biointerfaces, 2020, 194, 111173.

8. Chengde Liu, Cheng Liu*, Yu Gao, Fang Cheng, Gary G. Xiao, Jinyan Wang, and Xigao Jian*. Apatite Formation on Poly(aryl ether sulfone ketone) Surfaces by Means of Polydopamine Layers Functionalized with Phosphonate Groups. Adv. Mater. Interfaces 2018, 1800003.

9. Chengde Liu, Yizheng Li, Jinyan Wang, Cheng Liu*, Wentao Liu and Xigao Jian*. Improving Hydrophilicity and Inducing Bone-Like Apatite Formation on PPBES by Polydopamine Coating for Biomedical Application. Molecules 2018, 23, 1643.

10. Chengde Liu, Zhongxing Zhang, Kerh Li Liu, Xiping Ni, Jun Li*. Biodegradable thermogelling poly(ester urethane)s consisting of poly(1,4-butylene adipate), poly(ethylene glycol), and poly(propylene glycol). Soft Matter 2013, 9: 787–794.

11. Chengde Liu, Zhongxing Zhang, Xiao Liu, Xiping Ni, Jun Li*. Gelatin-based hydrogels with β-cyclodextrin as a dual functional component for enhanced drug loading and controlled release. RSC Advances 2013, 3, 25041-25049. 10.


 



Educational Experience

  • 2008.8-2013.9  

    新加坡国立大学       合成高分子生物材料       Doctoral Degree

  • 2006.9-2008.5  

    吉林大学       材料学       Master's Degree

  • 2002.9-2006.7  

    吉林大学       高分子材料工程       Bachelor's Degree

Work Experience

  • 2018.12-Now

    大连理工大学      副教授

  • 2014.12-2018.12

    大连理工大学      讲师

  • 2013.1-2014.3

    新加坡国立大学      research fellow

Address: No.2 Linggong Road, Ganjingzi District, Dalian City, Liaoning Province, P.R.C., 116024
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