LIU Chengde   

Associate Professor
Supervisor of Doctorate Candidates
Supervisor of Master's Candidates

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    柳承德,隶属于蹇锡高院士团队,医用高分子材料及临床应用研究中心副主任,首批教育部“全国高校黄大年式教师团队”核心成员,《表面技术》杂志青年编委。

    主要研究工作为杂萘联苯聚芳醚骨植入材料的合成及表面改性。通过分子结构设计、优化聚芳醚的合成方法及开发新型纯化技术,获得力学性能和生物学性能满足聚芳醚生物材料要求的医用杂萘联苯聚芳醚,进行中试实验研究。对聚芳醚进行生物功能化表面改性,改善了聚芳醚材料的生物相容性,并赋予其成骨活性,抗菌功能及局部治疗功能。Advanced Functional Materials、Chemical Engineering Journal、Bioactive Materials等国内外重要学术期刊上共发表论文40余篇、授权发明专利20余项。

 

研究方向:

1. 杂萘联苯聚芳醚生物材料合成及其应用研究

2. 医用碳纤维增强树脂基复合材料开发

3. 聚芳醚酮等生物医用材料表面改性研究

 

招生信息

 本生物材料研究小组属于蹇锡高院士科研团队,依托精细化工国家重点实验室等力争提供有竞争力的科研平台,并营造良好的氛围,用我们的力量托举每一位用心的青年才俊。热忱欢迎具有材料、化学、化工等知识背景的青年学子加入我们,进行创新实验或者攻读硕士研究生、博士研究生。


10篇代表性学术论文:

  • Xitong Cheng, Yizheng Li, Xiaoxue Chui, Zhonghua Xin, Zihan Ma, Pengxin Mei, Chengde Liu,* Xuemei Zhang,* Jinyan Wang,* and Xigao Jian.* Energetic Calcium Phosphate Nanominerals for Osteoporosis Treatment. Advanced Functional Materials, 2024: 2415906. 

  • Yizheng Li, Xitong Cheng, Xuemei Zhang, Zihan Ma, Chufan Deng, Chengde Liu,* Xigao Jian.* Biomimetic metal-phenolic network with cyclolactam hydrogel coating on PPENK implant facilitate bone repair. Chemical Engineering Journal, 2024, 486: 150234.

  • Yizheng Li, Chengde Liu,* Xitong Cheng, Jinyan Wang, Yue Pan, Cheng Liu, Shouhai Zhang, Xigao Jian.* PDA-BPs integrated mussel-inspired multifunctional hydrogel coating on PPENK implants for anti-tumor therapy, antibacterial infection and bone regeneration. Bioactive Materials, 2023, 27: 546–559.

  • Xitong Cheng, Xiao Yang, Chengde Liu,* Yizheng Li, Yangyang Zhang, Jinyan Wang,* Xingdong Zhang, and Xigao Jian. Stabilization of Apatite Coatings on PPENK Surfaces by Mechanical Interlocking to Promote Bioactivity and Osseointegration In Vivo. ACS Appl. Mater. Interfaces 2023, 15, 697−710.

  • Xitong Cheng, Yizheng Li, Wentao Liu, Shouhai Zhang, Chengde Liu,* Jinyan Wang,* Xigao Jian. Phosphonate-functionalized poly(phthalazinone ether ketones) induce the formation of apatite coatings for enhanced biocompatibility and osteogenic activity. ACS Applied Polymer Materials 2022, 4, 2562 .

  • Yizheng Li, Chengde Liu,* Xitong Cheng, Ali Zhang, Wentao Liu, Shouhai Zhang, Xigao Jian.* Tunicate inspired gelatin-based tough hydrogel wound dressing containing twisted phthalazinone with adhesive, self-healing and antibacterial properties. International Journal of Biological Macromolecules, 2022, 218, 639.

  • Chengde Liu, Liang Pan, Cheng Liu, Wentao Liu, Yizheng Li, Xitong Cheng and Xigao Jian.* Enhancing Tissue Adhesion and Osteoblastic Differentiation of MC3T3-E1 Cells on Poly(aryl ether ketone) by Chemically Anchored Hydroxyapatite Nanocomposite Hydrogel Coating. Macromolecular Bioscience 2021, 21(7), 2100078.

  • Wentao Liu, Han Wang, Cheng Liu, Jinyan Wang, Xitong Cheng, Chengde Liu,* Liyuan Qiao, Shouhai Zhang, Xigao Jian.* RhBMP-2 immobilized on poly(phthalazinone ether nitrile ketone) via chemical and physical modification for promoting in vitro osteogenic differentiation. Colloids and Surfaces B: Biointerfaces, 2020, 194, 111173.

  • Chengde Liu, Cheng Liu,* Yu Gao, Fang Cheng, Gary G. Xiao, Jinyan Wang, and Xigao Jian.* Apatite Formation on Poly(aryl ether sulfone ketone) Surfaces by Means of Polydopamine Layers Functionalized with Phosphonate Groups. Adv. Mater. Interfaces 2018, 1800003.

  • Chengde Liu, Zhongxing Zhang, Kerh Li Liu, Xiping Ni, Jun Li.* Biodegradable thermogelling poly(ester urethane)s consisting of poly(1,4-butylene adipate), poly(ethylene glycol), and poly(propylene glycol). Soft Matter 2013, 9: 787–794.


 



Educational Experience

  • 2008.8-2013.9  

    新加坡国立大学       合成高分子生物材料       Doctoral Degree

  • 2006.9-2008.5  

    吉林大学       材料学       Master's Degree

  • 2002.9-2006.7  

    吉林大学       高分子材料工程       Bachelor's Degree

Work Experience

  • 2018.12-Now

    大连理工大学      副教授

  • 2014.12-2018.12

    大连理工大学      讲师

  • 2013.1-2014.3

    新加坡国立大学      research fellow

Address: No.2 Linggong Road, Ganjingzi District, Dalian City, Liaoning Province, P.R.C., 116024
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