张蓉

个人信息Personal Information

高级工程师

硕士生导师

性别:女

毕业院校:大连理工大学

学位:博士

所在单位:化工学院

学科:应用化学

办公地点:理工西部校区实验楼F308

联系方式:rzhang@dlut.edu.cn

电子邮箱:rzhang@dlut.edu.cn

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Copper-Catalyzed Direct Oxidative C-H Amination of Benzoxazoles with Formamides or Secondary Amines under Mild Conditions

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论文类型:期刊论文

发表时间:2011-07-01

发表刊物:JOURNAL OF ORGANIC CHEMISTRY

收录刊物:SCIE、EI、PubMed

卷号:76

期号:13

页面范围:5444-5449

ISSN号:0022-3263

摘要:A facile, efficient, and practical method for copper-catalyzed direct C-H amination of benzoxazoles with formamides or secondary amines has been developed. The system can be performed in the absence of external base and only requires O(2) or even air as oxidant. A variety of substituted benzoxazol-2-amines were synthesized with moderate to excellent yield.