张蓉

个人信息Personal Information

高级工程师

硕士生导师

性别:女

毕业院校:大连理工大学

学位:博士

所在单位:化工学院

学科:应用化学

办公地点:理工西部校区实验楼F308

联系方式:rzhang@dlut.edu.cn

电子邮箱:rzhang@dlut.edu.cn

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Ready synthesis of free N-H 2-arylindoles via the copper-catalyzed amination of 2-bromo-arylacetylenes with aqueous ammonia and sequential intramolecular cyclization

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论文类型:期刊论文

发表时间:2011-07-07

发表刊物:ORGANIC & BIOMOLECULAR CHEMISTRY

收录刊物:SCIE、EI、PubMed、Scopus

卷号:9

期号:13

页面范围:4983-4986

ISSN号:1477-0520

摘要:A wide range of free N-H 2-arylindoles were synthesised via the copper(II)-catalyzed amination of 2-bromo-arylacetylenes with aqueous ammonia and sequential intramolecular cyclization. The convenience and atom economy of aqueous ammonia, and the low cost of the copper catalytic system make this protocol readily superior in practical application.