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论文类型：期刊论文

发表时间：2008-07-01

发表刊物：NONLINEAR ANALYSIS-REAL WORLD APPLICATIONS

收录刊物：SCIE、EI

卷号：9

期号：3

页面范围：1068-1077

ISSN号：1468-1218

关键字：bilevel identification; multi-stage impulsive system; optimal algorithm; fed-batch cultures

摘要：Considering the abrupt jump of the substrate and different characters of the bacterial in the lag phase, the exponential phase and the stationary phase this paper proposes the multi-stage nonlinear impulsive system for the fed-batch fermentation from glycerol to 1,3-propanediol (1,3-PD) and establishes the bilevel identification system for its sensitive parameters. The properties of the solutions for the nonlinear multi-stage dynamical system are investigated and identifiability of the parameters is proved. Finally an optimal algorithm is constructed to obtain the optimal solution of the identification model and the numerical example is then discussed to illustrate the algorithm. (C) 2007 Elsevier Ltd. All rights reserved.