Release Time:2019-03-11  Hits:

Indexed by: Conference Paper

Date of Publication: 2011-06-08

Included Journals: Scopus、CPCI-S、EI

Volume: 441

Page Number: 398-402

Key Words: Styryl dye; Colorific probe; Fluorescent DNA probe; ICT

Abstract: The synthesis and characteristics of a new styryl colorific and fluorescent dual signal probe for DNA are described. Sty-HPy shows a high fluorescence enhancement (> 35-fold) in conjunction with a visible colorific change (45 nm red-shift) when bound to dsDNA. The large Stokes shift (140 nm) and sensitive colorific response to DNA are both attributed to the rational design of intramolecular charge transfer (ICT) intra Sty-HPy.