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A Colorific and Fluorescent Dual Signal Probe for DNA

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Indexed by:会议论文

Date of Publication:2011-06-08

Included Journals:EI、CPCI-S、Scopus

Volume:441

Page Number:398-402

Key Words:Styryl dye; Colorific probe; Fluorescent DNA probe; ICT

Abstract:The synthesis and characteristics of a new styryl colorific and fluorescent dual signal probe for DNA are described. Sty-HPy shows a high fluorescence enhancement (> 35-fold) in conjunction with a visible colorific change (45 nm red-shift) when bound to dsDNA. The large Stokes shift (140 nm) and sensitive colorific response to DNA are both attributed to the rational design of intramolecular charge transfer (ICT) intra Sty-HPy.

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